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Novilytic Launches Proteometer-CV Kit for Rapid Charge Variant Analysis

Charge Variant Kit revolutionizes antibody development with time savings and efficiency


WEST LAFAYETTE, Ind. (MONTH, DAY, 2024) – Novilytic, an innovator in molecular recognition technology, is excited to announce the release of its Proteometer-CV Kit. This new consumables kit offers groundbreaking advancements in charge variant (CV) analysis. It is specifically designed for scientists focused on developing monoclonal antibodies (mAbs), bispecific antibodies, or fusion proteins with a human Fc region.

 

Unlike traditional CV methods that demand extensive sample preparation, purification, and sophisticated instrumentation, the Proteometer-CV allows for rapid analysis directly from clarified fermentation broth in less than 25 minutes without sample preparation. The assay works with a dual pump HPLC equipped with a fluorescence detector.  The technology of the Proteometer-CV assay significantly reduces the reliance on conventional methods that require Protein A purification.

 

Key Features and Benefits:

  • No Protein A Purification Required: Streamlines the process, reducing sample handling and associated errors

  • Low Sample Requirements: Efficient analysis with minimal sample volume required

  • Rapid Serial Analysis: Facilitates streamlined processing for higher throughput than Pro A-iCEF or Pro A-HPLC

  • Simplified Workflow: Easy mobile phase preparation with provided components

  • In-Broth Technology: The only solution performing CV analysis directly in clarified fermentation broth, ensuring sample integrity

  • Rapid Turnaround: Complete analysis in 25 minutes from sampling to data

  • Plug-and-Play: Comes with all components needed for analysis with minimal method development


“We are proud to introduce the Proteometer-CV as a breakthrough technology in the field of antibody development,” said Paul Dreier, BSc., MBA, Novilytic CEO. “This kit addresses a critical bottleneck in drug development processes by providing a fast, accurate, cost-effective CV analysis without sample preparation. It represents a significant advancement in our mission to provide technology that empowers scientists to accelerate the development of lifesaving medicines.”

 

The Proteometer-CV Kit includes all necessary components and easy-to-follow instructions to simplify and expedite the analysis process.

 

About Novilytic: 

Novilytic is a leader in molecular recognition technology. Their Proteometer product line is revolutionizing drug development and clone selection by eliminating sample preparation steps that were previously industry-standard. Their transformational technology fundamentally changes mAb production by providing near-real-time molecular structure analysis. This reduces the time and cost of drug development and ultimately helps bring lifesaving treatments to the market faster. For more information, visit Novilytic.com.

 

Photo of the Proteometer-CV

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