THE CANARY IN
THE FERMENTOR
Eliminate Sample Prep & Method Development
SOLUTIONS
Proteometer-L Kit
Identifies & quantifies titer + relative aggregate content in clarified fermentation broth, in 10 mins
For mAbs, multi-specifics, recombinant proteins containing an Fc domain
Proteometer-UFT Kit
Runs at-line titer measurements in under 90 seconds
For mAbs, multi-specifics, recombinant proteins containing an FC domain
ABOUT
Novilytic's Proteometer® product line streamlines drug development and clone selection by eliminating sample preparation steps.
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“Canary in the coal mine” refers to using birds to detect odorless but highly poisonous carbon monoxide gas to keep miners safe. Novilytic has applied this same premise to pharmaceutical laboratories.
Our nanotechnology acts as “The Canary in the Fermentor” by allowing scientists to monitor batch quality in-process.
The Proteometer-L, aka “proteoform meter,” performs at-line, real-time batch analysis - for human or humanized mAbs, multipecifics, or proteins containing an Fc domain - roughly every 10 minutes and eliminates the need for sample preparation and method development.
TESTIMONIALS
"We use the Proteometer-L Kit for the rapid analysis of mAbs and bispecifics for titer and aggregate content from cell-free filtrate samples.
It eliminates sample preparation steps, Protein A purification, and mass spectrometry analysis steps.
I would recommend the Proteometer to any pharmaceutical company to quickly and accurately quantitate titer and aggregate content."
Harsha Gunawardena
Senior Principal Scientist
Johnson & Johnson
“Novilytic’s Proteometer is a disruptive breakthrough that finally solves the FDA's requirement to continuously monitor t-mAb (therapeutic mAbs) proteoforms during fermentation.
The approach improves product safety, reduces COPQ and post-release testing, and paves the way for real-time product release, reducing inventory costs.”
Martin Long, BSc.
President & CEO
Performance Validation, Inc.
(Analytical Sciences Business, Brooks Life Sciences, Thermo, Perkin Elmer)
Analytical testing in DD & clone selection is 5-10 days
Proteometer trims this to one day
Savings = $800K - $1.8M per clone selection DoE